The potential impact of CBD on neurodevelopmental conditions
Cannabidiol (CBD) was initially discovered in 1940 and has since been studied for its potential uses, receiving its own awareness day in 2018. Differing from THC (which is found in higher concentrations in marijuana), CBD is non-psychoactive and does not cause a high, meaning it could be used without causing intoxication. Since this discovery, there has been growing interest in its potential therapeutic use.
There is a need for further study of its use and side effects before it can be a viable option, but there have been some positive indications of its future potential in management of neurodevelopmental conditions such as Autism and ADHD.
Table of contents
- What are neurodevelopmental conditions?
- CBD and Autism
- CBD and ADHD
- What are the risks with CBD use?
- Why does this matter to us?
- Interested in an assessment for a neurodevelopmental condition?
What are neurodevelopmental conditions?
Neurodevelopmental conditions are a categorisation of conditions affecting the development of the brain and nervous system. This includes Autism and ADHD as well as specific learning conditions such as dyspraxia, dyslexia and dyscalculia. Also included in the category are Epilepsy and Tourette Syndrome.
CBD and Autism
Autism is one neurodevelopmental condition that has been studied in relation to CBD use to help manage a variety of associated presentations of the condition.
Adults have found in small studies that CBD had a positive impact alongside their other medications but, with little known about medication interactions, this is not something we would clinically advise. In a study of children with autism, parents reported improvements in self-injury and rage (67%), hyperactivity (68%), sleep problems (71%), and anxiety (47%) after using CBD. Mild side effects were noted, highlighting the need for larger-scale research to assess long-term safety and effectiveness.
CBD and ADHD
There have been limited studies on the impact of CBD on ADHD, but interest has been growing in recent years.
Studies have found that, while results are limited, there have been positive responses when CBD is used in the form of cannabis-based medicinal products. One study of adults with ADHD found that 90% reported improved attention, 63% saw improvements in hyperactivity, and 62% in impulsiveness. More study is needed before this could be a recommended pathway, however, as this is not a management option licensed for mental disorders in the UK.
What are the risks with CBD use?
The reason more research is needed into CBD as a management option for neurodevelopmental conditions is that there are associated risks and limitations based on the studies we can currently reference. In order to have a clear understanding of its use, we would need to know more about its side effects, interactions with other medications, and need to develop clear guidelines to ensure product quality.
We know that CBD can interact with other medications and impact their effectiveness, with examples such as blood thinners, so more research is necessary to ensure patient safety. There have also been limits and changes to the recommended daily intake of CBD, something which we would need more clear guidelines on to be able to recommend it safely.
This is why CBD is not currently licensed for use in managing ADHD or Autism in the UK and why we would not recommend it as a management option. If you are using CBD alongside other medications, it is extremely important that you inform your clinician.
Why does this matter to us?
At Clinical Partners, understanding the best evidence-based practices for supporting our patients is crucial to what we do, and we’re always looking to improve our understanding of neurodevelopmental conditions and their management. As part of our mission to offer the best possible resources to our patients, we aim to keep a close eye on studies that may help us to offer up to date guidance.
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Clinically reviewed
- Dr Angus McLellan