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Clinical Partners

Author: Clinical Partners Published: 28 August, 2026

Tags: Bipolar disorder, Adults

For both clinicians and patients, the cause of a mental health condition can be key to management and offers greater understanding of the condition itself. Bipolar disorder is an example of a condition that can be inherited. It has been found that genetic factors are one of the main causes of the condition.

It is not just limited to hereditary causes, however. Several other factors can cause bipolar disorder, including environmental factors, substance use, and hormonal changes for mothers during pregnancy or after birth.

This guide covers how bipolar disorder can be inherited, the various causes, and how the disorder can be treated.

About bipolar disorder

Bipolar disorder is a mental health condition that affects your mood. It causes extreme shifts that can range from episodes of intense highs (mania or hypomania) to deep lows (depression). These changes can impact your energy levels, behaviour, and ability to carry out day-to-day tasks.

Symptoms vary from person to person, but during a manic phase, someone might feel unusually elated. They may:

  • have racing thoughts

  • struggle to sleep

  • take risks they wouldn’t normally consider

In contrast, a depressive episode may bring:

  • overwhelming sadness

  • low energy

  • difficulty concentrating

  • feelings of hopelessness

Genetic factors of bipolar disorder

Research suggests that bipolar disorder can run in families. If you have a parent, sibling, or close relative with bipolar disorder, your chances of developing the condition are higher than those of someone with no family history. However, this doesn’t mean it’s guaranteed to be passed on.

There are also usually non-genetic factors involved. While no single gene has been found to cause the condition outright, certain genes may increase vulnerability. It’s also possible for someone with no family history to develop bipolar disorder.

Understanding the genetic link can help identify patterns within families and guide early support or diagnosis. But it’s just one piece of the puzzle. Many other influences can contribute to how and when the condition develops.

Other causes of bipolar disorder

While genetics can certainly play a part, bipolar disorder often comes about as a result of a combination of different factors. These may interact over time, contributing to the onset or worsening of symptoms. Below are some of the more common non-genetic causes.

Environmental factors

Stressful or traumatic life events can sometimes trigger the symptoms of bipolar disorder, particularly in those who may already be more vulnerable. This might include emotionally challenging situations, such as bereavement, childhood trauma, financial difficulties, or high-pressure life changes.

Substances

Certain drugs and alcohol can influence mood in ways that mimic or worsen bipolar symptoms. Some substances may trigger a high that resembles mania, while others can increase feelings of depression or anxiety. In some cases, substance use may make it harder to recognise or diagnose bipolar disorder accurately.

Pregnancy

For some people, symptoms of bipolar disorder can begin during pregnancy or after giving birth. This is a period when emotional and hormonal changes are already heightened. These factors can intensely amplify the symptoms. The condition is known as perinatal or postpartum bipolar disorder. Early diagnosis and treatment are important for both the parent and the baby.

Co-existing mental health conditions

Bipolar disorder can often occur alongside other mental health conditions, such as anxiety, depression, ADHD, or post-traumatic stress disorder (PTSD). It may also be confused with conditions like borderline personality disorder (BPD), due to some overlapping symptoms such as mood swings or impulsivity. A thorough assessment is essential to make sure the right diagnosis and treatment plan are in place.

How is bipolar disorder treated?

Bipolar disorder is a long-term condition, but with the right support and treatment, many people can manage their symptoms and lead fulfilling lives. Treatment often involves a combination of approaches.

The two most common and effective treatments for bipolar disorder include:

Talking therapy

Psychological therapies can play a key role in helping people understand their thoughts, feelings, and behaviours. Cognitive behavioural therapy (CBT), for example, can help someone recognise early signs of mood changes and develop coping strategies. Interpersonal therapy and family-focused therapy may also support people in managing relationships and navigating challenges that come with the condition.

Therapy can also be helpful for working through difficult life experiences that may contribute to mood episodes. This approach offers space to explore episodes safely with a trained professional.

Medication

Medication is often used to help stabilise mood and reduce the frequency and severity of episodes. Common medications include mood stabilisers such as lithium, antipsychotics, or, in some cases, antidepressants. The right medication will vary depending on the type of bipolar disorder and the person’s symptoms.

It may take time to find the most effective medication and dosage. This is why regular follow-up and support from a psychiatrist or GP is important.

Looking for support with bipolar disorder?

If you are looking for an assessment to potentially diagnose bipolar disorder, or want to explore treatment options tailored to your experiences, you can contact us for a free initial conversation.